Biomechanics of HIV and Immune Cell Interactions Investigated using Magnetic Tweezer Force Spectroscopy
نویسندگان
چکیده
منابع مشابه
synthesis of amido alkylnaphthols using nano-magnetic particles and surfactants
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Living biological cells are highly complex, multifunctional systems whose physical attributes are relatively unknown. Critical functions involving plasticity of cell morphology, connectivity and response to stimuli are proposed to be fundamentally related to the micromechanical character and the ability of the cell to exert directed mechanical signaling. Unique abilities of atomic force microsc...
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Relatively recently, the Atomic Force Microscope (AFM) emerged as a powerful tool for single molecule nanomechanical investigations. Parameters that can be measured by force spectroscopy using AFM, such as the force and total mechanical extension required to break bonds between various proteins can yield valuable insights into the nature of the bond (zippering vs. highly localized binding site)...
متن کاملBiomechanics of the anterior human corneal tissue investigated with atomic force microscopy.
PURPOSE To investigate the biomechanics of the anterior human corneal stroma using atomic force microscopy (AFM). METHODS AFM measurements were performed in liquid on the anterior stroma of human corneas, after gently removing the epithelium, using an atomic force microscope in the force spectroscopy mode. Rectangular silicon cantilevers with tip radius of 10 nm and spring elastic constants o...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2018
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2017.11.652